Back to search

Article

Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns

2018-12-10

Abstract excerpt

<h4>Background</h4> Inflammatory processes contribute to the pathophysiology of multiple chronic conditions. Genetic factors play a crucial role in modulating the inflammatory load, but the exact mechanisms are incompletely understood. <h4>Methods</h4> To add understanding to the molecular mechanisms in inflammation, we performed a genome-wide association study (GWAS) on 16 circulating cytokines and cell adhesio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
51f25ccc-a3f6-5b2f-8022-217bb4686509
DOI
10.1101/491852
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in FinnsDOI 10.1101/491852
Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in FinnsSemantic proximity
Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levelsSemantic proximity
Quantitative genetic analysis of cellular adhesion molecules: the Fels Longitudinal Study.Semantic proximity
Genetic variants in ABO blood group region, plasma soluble E-selectin levels and risk of type 2 diabetes.Semantic proximity
Associations of vascular endothelial growth factor (VEGF) with adhesion and inflammation molecules in a healthy population.Semantic proximity
Association of variation at the ABO locus with circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin: a meta-analysis.Semantic proximity
ABO blood group associations with markers of endothelial dysfunction in the Multi-Ethnic Study of Atherosclerosis.Semantic proximity
Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin.Semantic proximity
A variant in the ABO gene explains the variation in soluble E-selectin levels-results from dense genotyping in two independent populations.Semantic proximity
Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci.Semantic proximity
Genetic and environmental determinants of variation of soluble adhesion molecules.Semantic proximity
Characterization of the human ABO genotypes and their association to common inflammatory and cardiovascular diseases in the UK Biobank.Semantic proximity
Select a neighboring publication to make it the new centre.