Article
The mutation of the LEW.1AR1-iddm rat maps to the telomeric end of rat chromosome 1.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2008
Weiss Heike, Arndt Tanja, Jörns Anne, Lenzen Sigurd, Cuppen Edwin, Hedrich Hans J, Tiedge Markus, Wedekind Dirk
Abstract excerpt
The LEW.1AR1-iddm rat is an animal model of human type 1 diabetes mellitus (T1DM) with an autosomal recessive mode of inheritance. T1DM susceptibility loci could be localized on chromosome (RNO) 20 in the major histocompatibility complex region (Iddm1) and on RNO1 (Iddm8, Iddm9) in a BN backcross...
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