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Article

The mutation of the LEW.1AR1-iddm rat maps to the telomeric end of rat chromosome 1.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2008

Weiss Heike, Arndt Tanja, Jörns Anne, Lenzen Sigurd, Cuppen Edwin, Hedrich Hans J, Tiedge Markus, Wedekind Dirk

Abstract excerpt

The LEW.1AR1-iddm rat is an animal model of human type 1 diabetes mellitus (T1DM) with an autosomal recessive mode of inheritance. T1DM susceptibility loci could be localized on chromosome (RNO) 20 in the major histocompatibility complex region (Iddm1) and on RNO1 (Iddm8, Iddm9) in a BN backcross cohort. In this study the impact of the different susceptibility regions on diabetes development was investigated in a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18357488
DOI: 10.1007/s00335-008-9102-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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