Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative trait loci for lipid metabolism in the study of OLETF x (OLETF x Fischer 344) backcross rats.

Clinical and experimental pharmacology & physiology - 1 Nov 2000

Yamasaki Y, Watanabe T K, Okuno S, Ono T, Oga K, Mizoguchi-Miyakita A, Goto Y, Shinomiya H, Momota H, Miyao H, Hayashi I, Asai T, Suzuki M, Harada Y, Hishigaki H, Wakitani S, Takagi T, Nakamura Y, Tanigami A

Abstract excerpt

1. The Otsuka Long-Evans Tokushima Fatty (OLETF) rat is a model of type II diabetes with accompanying dyslipidaemia and obesity. 2. To define chromosomal intervals associated with obesity (abdominal fat weight and plasma leptin levels), dyslipidaemia (plasma triglyceride, cholesterol and free fat...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol
Share to Hyperlipidemias

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipid Metabolism

Share to Lipids

Share to Quantitative Trait, Heritable

Share to Rats, Inbred F344

Share to Rats, Long-Evans

Share to Triglycerides

Source

Identifiers

PMID: 11071303
DOI: 10.1046/j.1440-1681.2000.03353.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11071303-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative trait loci for lipid metabolism in the study of OLETF x (OLETF x Fischer 344) backcross rats.PMID 11071303Read ↗

Genetic dissection of "OLETF," a rat model for non-insulin-dependent diabetes mellitus: quantitative trait locus analysis of (OLETF x BN) x OLETF.Semantic proximity Read ↗

A < 1.7 cM interval is responsible for Dmo1 obesity phenotypes in OLETF rats.Semantic proximity Read ↗

Genetic determinants of plasma triglyceride levels in (OLETF x BN) x OLETF backcross rats.Semantic proximity Read ↗

Effects of Dmo1 on obesity, dyslipidaemia and hyperglycaemia in the Otsuka Long Evans Tokushima Fatty strain.Semantic proximity Read ↗

Single-allele correction of the Dmo1 locus in congenic animals substantially attenuates obesity, dyslipidaemia and diabetes phenotypes of the OLETF rat.Semantic proximity Read ↗

Substitution of Dmo1 with normal alleles results in decreased manifestation of diabetes in OLETF rats.Semantic proximity Read ↗

Genetic dissection of "OLETF", a rat model for non-insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Genetic evidence for obesity loci involved in the regulation of body fat distribution in obese type 2 diabetes rat, OLETF.Semantic proximity Read ↗

Mutated G-protein-coupled receptor GPR10 is responsible for the hyperphagia/dyslipidaemia/obesity locus of Dmo1 in the OLETF rat.Semantic proximity Read ↗

X-linked locus is responsible for non-insulin-dependent diabetes mellitus in the OLETF rat.Semantic proximity Read ↗

Genetic analysis of non-insulin-dependent diabetes mellitus in the Otsuka Long-Evans Tokushima Fatty rat.Semantic proximity Read ↗

Mapping and characterization of quantitative trait loci for non-insulin-dependent diabetes mellitus with an improved genetic map in the Otsuka Long-Evans Tokushima fatty rat.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.