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Article

piggyBac can bypass DNA synthesis during cut and paste transposition.

The EMBO journal - 9 Apr 2008

Mitra Rupak, Fain-Thornton Jennifer, Craig Nancy L

Abstract excerpt

DNA synthesis is considered a defining feature in the movement of transposable elements. In determining the mechanism of piggyBac transposition, an insect transposon that is being increasingly used for genome manipulation in a variety of systems including mammalian cells, we have found that DNA synthesis can be avoided during piggyBac transposition, both at the donor site following transposon excision and at the...

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Identifiers

PMID: 18354502
DOI: 10.1038/emboj.2008.41
PMCID: PMC2323262

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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