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Article

piggyBac-based insertional mutagenesis in the presence of stably integrated P elements in Drosophila.

Proceedings of the National Academy of Sciences of the United States of America - 24 Jun 2003

Hacker Udo, Nystedt Sverker, Barmchi Mojgan Padash, Horn Carsten, Wimmer Ernst A

Abstract excerpt

P element-mediated mutagenesis has been used to disrupt an estimated 25% of genes essential for Drosophila adult viability. Mutation of all genes in the fly genome, however, poses a problem, because P elements show significant hotspots of integration. In addition, advanced screening scenarios oft...

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Identifiers

PMID: 12802016
DOI: 10.1073/pnas.1230526100
PMCID: PMC164654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12802016-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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