Genetic variations of human neuropsin gene and psychiatric disorders: polymorphism screening and possible association with bipolar disorder and cognitive functions.

doi:10.1038/npp.2008.29

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Article

Genetic variations of human neuropsin gene and psychiatric disorders: polymorphism screening and possible association with bipolar disorder and cognitive functions.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Dec 2008

Izumi Aiko, Iijima Yoshimi, Noguchi Hiroko, Numakawa Tadahiro, Okada Takeya, Hori Hiroaki, Kato Tadafumi, Tatsumi Masahiko, Kosuga Asako, Kamijima Kunitoshi, Asada Takashi, Arima Kunimasa, Saitoh Osamu, Shiosaka Sadao, Kunugi Hiroshi

Abstract excerpt

Human neuropsin (NP) (hNP) has been implicated in the progressive change of cognitive abilities during primate evolution. The hNP gene maps to chromosome 19q13, a region reportedly linked to schizophrenia and bipolar disorder. Therefore, hNP is a functional and positional candidate gene for association with schizophrenia, mood disorders, and cognitive ability. Polymorphism screening was performed for the entire...

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PMID: 18354391
DOI: 10.1038/npp.2008.29

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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