Article
Chromosome 13q13-q14 locus overlaps mood and psychotic disorders: the relevance for redefining phenotype.
European journal of human genetics : EJHG - 1 Aug 2009
Maziade Michel, Chagnon Yvon C, Roy Marc-André, Bureau Alexandre, Fournier Alain, Mérette Chantal
Abstract excerpt
The nosology of major psychoses is challenged by the findings that schizophrenia (SZ) and bipolar disorder (BP) share several neurobiological, neuropsychological and clinical phenotypic characteristics. Moreover, several vulnerability loci or genes may be common to the two DSM disorders. We previously reported, in a sample of 21 kindreds (sample 1), a genome-wide suggestive linkage in 13q13-q14 with a common...
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