Article
Persistence of transmitted drug resistance among subjects with primary human immunodeficiency virus infection.
Journal of virology - 1 Jun 2008
Little Susan J, Frost Simon D W, Wong Joseph K, Smith Davey M, Pond Sergei L Kosakovsky, Ignacio Caroline C, Parkin Neil T, Petropoulos Christos J, Richman Douglas D
Abstract excerpt
Following interruption of antiretroviral therapy among individuals with acquired drug resistance, preexisting drug-sensitive virus emerges relatively rapidly. In contrast, wild-type virus is not archived in individuals infected with drug-resistant human immunodeficiency virus (HIV) and thus cannot emerge rapidly in the absence of selective drug pressure. Fourteen recently HIV-infected patients with transmitted...
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