Article
Persistence of primary drug resistance among recently HIV-1 infected adults.
AIDS (London, England) - 20 Aug 2004
Barbour Jason D, Hecht Frederick M, Wrin Terri, Liegler Teri J, Ramstead Clarissa A, Busch Michael P, Segal Mark R, Petropoulos Christos J, Grant Robert M
Abstract excerpt
OBJECTIVES: Primary, or transmitted, drug resistance is common among treatment naive patients recently infected with HIV-1, and impairs response to anti-retroviral therapy. We previously observed that patients with secondary resistance (developed in response to anti-retroviral treatment) who chose to stop an anti-retroviral regimen experience rapid overgrowth of drug resistant viruses by wild-type virus of higher...
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