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Article

Persistence of primary drug resistance among recently HIV-1 infected adults.

AIDS (London, England) - 20 Aug 2004

Barbour Jason D, Hecht Frederick M, Wrin Terri, Liegler Teri J, Ramstead Clarissa A, Busch Michael P, Segal Mark R, Petropoulos Christos J, Grant Robert M

Abstract excerpt

OBJECTIVES: Primary, or transmitted, drug resistance is common among treatment naive patients recently infected with HIV-1, and impairs response to anti-retroviral therapy. We previously observed that patients with secondary resistance (developed in response to anti-retroviral treatment) who chose to stop an anti-retroviral regimen experience rapid overgrowth of drug resistant viruses by wild-type virus of higher...

Topics

Adult
Anti-Retroviral Agents
CD4 Lymphocyte Count
Drug Resistance, Viral
Genes, pol
Genotype
HIV Infections
HIV Protease Inhibitors
HIV-1
Humans
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Viral

Reverse Transcriptase Inhibitors

Virus Replication

Source

Identifiers

PMID: 15280779
DOI: 10.1097/01.aids.0000131391.91468.ff

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