Article
Reversal periods and patterns from drug-resistant to wild-type HIV type 1 after cessation of anti-HIV therapy.
AIDS research and human retroviruses - 1 Jan 2007
Bi Xiuqiong, Gatanaga Hiroyuki, Koike Kazuhiko, Kimura Satoshi, Oka Shinichi
Abstract excerpt
Anti-HIV drug-resistant virus reverts to wild type following discontinuation of antiretroviral therapy (ART). This study aimed to determine the reversal period. ART was discontinued in 16 patients harboring drug-resistant viruses. Resistant mutations of reverse transcriptase (RT) and protease (PR) genes of plasma- and peripheral blood mononuclear cells (PBMC)-derived viruses were examined by direct sequencing...
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