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Article

Incorporating prior information into association studies.

Bioinformatics (Oxford, England) - 15 Jun 2012

Darnell Gregory, Duong Dat, Han Buhm, Eskin Eleazar

Abstract excerpt

UNLABELLED: Recent technological developments in measuring genetic variation have ushered in an era of genome-wide association studies which have discovered many genes involved in human disease. Current methods to perform association studies collect genetic information and compare the frequency of variants in individuals with and without the disease. Standard approaches do not take into account any information on...

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PMID: 22689754
DOI: 10.1093/bioinformatics/bts235
PMCID: PMC3371867

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