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Article

Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice.

Developmental biology - 1 May 2008

Guttormsen Jillian, Koster Maranke I, Stevens John R, Roop Dennis R, Williams Trevor, Winger Quinton A

Abstract excerpt

Summary Sentence: Conditional ablation of AP-2 gamma results in a delay in skin development and abnormal expression of p63, K14, K1, filaggrin, repetin and secreted Ly6/Plaur domain containing 1, key genes required for epidermal development and differentiation. The development of the epidermis, a stratified squamous epithelium, is dependent on the regulated differentiation of keratinocytes. Differentiation begins...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18353300
DOI: 10.1016/j.ydbio.2008.02.017
PMCID: PMC2435508

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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