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Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression

1 Mar 2007

Abstract excerpt

The mammalian epidermis is the first line of defense against external environmental challenges including dehydration. The epidermis undergoes a highly intricate developmental program in utero, transforming from a simple to a complex stratified epithelium. During this process of stratification and differentiation, epidermal keratinocytes express a defined set of structural proteins, mainly keratins, whose...

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PMID: 17330888
DOI: 10.1002/dvdy.21099

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