Article
Epidermal differentiation: transgenic/knockout mouse models reveal genes involved in stem cell fate decisions and commitment to differentiation.
The journal of investigative dermatology. Symposium proceedings - 1 Dec 2002
Koster Maranke I, Huntzinger Kimberly A, Roop Dennis R
Abstract excerpt
Epidermal development and differentiation are similar processes and therefore the study of one is likely to provide insight into the other. The signaling cascades required for epidermal differentiation are largely unknown. Recent evidence, however, has implicated two proteins, p63 and c-Myc, in different stages of epidermal development and differentiation. p63 was shown to be required for embryonic epidermal...
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