Article
TAp63alpha induces AP-2gamma as an early event in epidermal morphogenesis.
Developmental biology - 1 Jan 2006
Koster Maranke I, Kim Soeun, Huang Jian, Williams Trevor, Roop Dennis R
Abstract excerpt
Epidermal morphogenesis begins with the commitment of the single-layered surface ectoderm to initiate a stratification program, a process that requires the expression of the transcription factor TAp63alpha. To determine the molecular mechanism by which TAp63alpha induces genes associated with the commitment to stratification, such as K14, we have used a combination of in vitro and in vivo approaches. Our initial...
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