Article
Mitf contributes to melanosome distribution and melanophore dendricity.
Pigment cell & melanoma research - 1 Feb 2008
Kawasaki Akiha, Kumasaka Mayuko, Satoh Akira, Suzuki Makoto, Tamura Koji, Goto Toshiyasu, Asashima Makoto, Yamamoto Hiroaki
Abstract excerpt
Mitf is a transcription factor of the basic/helix-loop-helix/leucine-zipper family which is indispensable for development of melanocytes and the retinal pigment epithelium. Our previous work using Xenopus laevis as a model system suggested that Mitf regulates melanosome dispersal in vivo though whether this was via melanosome transport or melanophore dendricity was not obvious. To better understand the role of...
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