Article

Loss of MITF activity leads to emergent cell states from the melanocyte stem cell lineage

2025-12-25

Abstract excerpt

How embryonic cells generate large clones of cells in the adult represents a fundamental question in biology. Here using melanocyte stem cells (McSCs) in the zebrafish as a model we explore the function of the master melanocyte transcription factor (MITF) in safeguarding McSCs in embryonic development and their potential to pigment large clones in the adult. MITF is well known is for its role in the specification...

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Literature Corpus work: dd5a8ab8-4783-58e2-a34c-aa6b9272c254
DOI: 10.64898/2025.12.23.695681

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