Article
Melanophilin regulates dendritogenesis in melanocytes for feather pigmentation.
Communications biology - 17 May 2024
Kim Dong-Hwan, Lee Joonbum, Ko Jae-Kyun, Lee Kichoon
Abstract excerpt
Limited studies using animal models with a few natural mutations in melanophilin (Mlph) provided partial functions of Mlph in melanosome trafficking. To investigate cellular functions of Mlph, especially ZnF motif of Mlph, we analyzed all three Mlph knockout (KO) quail lines, one and two base pair (bp) deletions as models for total KO, and three bp deletion causing deletion of one Cysteine (C84del) in the ZnF...
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