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Article

Epigenetic Modification of the Norepinephrine Transporter Gene in Postural Tachycardia Syndrome

22 Jun 2012

Abstract excerpt

OBJECTIVE: The postural tachycardia syndrome (POTS) has multiple symptoms, chief among which are tachycardia, weakness, and recurrent blackouts while standing. Previous research has implicated dysfunction of the norepinephrine transporter. A coding mutation in the norepinephrine transporter gene (SLC6A2) sequence has been reported in 1 family kindred only. The goal of the present study was to further characterize...

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PMID: 22723437
DOI: 10.1161/atvbaha.111.244343

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