Article
Regulation of the smooth muscle contractile phenotype by nonmuscle myosin.
Journal of muscle research and cell motility - 1 Jan 2007
Ogut Ozgur, Yuen Samantha L, Brozovich Frank V
Abstract excerpt
The contractile phenotype of a smooth muscle can broadly be classified as phasic or tonic. Following activation, phasic smooth muscle exhibits an initial period of rapid force activation, following which force falls to a lower steady state level. In contrast, force generated by tonic smooth muscle rises slowly to a sustained steady state. The differences in contractile patterns cannot be explained by the time...
Topics
- Animals
- Calcium
- Humans
- Muscle Contraction
- Muscle Tonus
- Muscle, Smooth
- Myosin Light Chains
- Nonmuscle Myosin Type IIB
- Phenotype
- Phosphorylation
