Article
Forced expression of essential myosin light chain isoforms demonstrates their role in smooth muscle force production.
The Journal of biological chemistry - 3 Dec 1999
Huang Q Q, Fisher S A, Brozovich F V
Abstract excerpt
The molecular determinants of the contractile properties of smooth muscle are poorly understood, and have been suggested to be controlled by splice variant expression of the myosin heavy chain near the 25/50-kDa junction (Kelley, C. A., Takahashi, M., Yu, J. H., and Adelstein, R. S. (1993) J. Biol. Chem. 268, 12848-12854) as well as by differences in the expression of an acidic (MLC(17a)) and a basic (MLC(17b))...
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