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Article

Protein kinase network in the regulation of phosphorylation and dephosphorylation of smooth muscle myosin light chain.

Molecular and cellular biochemistry - 1 Jun 2003

Hirano Katusya, Derkach Dmitry N, Hirano Mayumi, Nishimura Junji, Kanaide Hideo

Abstract excerpt

The contraction of smooth muscle is regulated primarily by intracellular Ca2+ signal. It is well established that the elevation of the cytosolic Ca2+ level activates myosin light chain kinase, which phosphorylates 20 kDa regulatory myosin light chain and activates myosin ATPase. The simultaneous measurement of cytosolic Ca2+ concentration and force development revealed that the alteration of the Ca2+-sensitivity...

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PMID: 12870661
DOI: 10.1023/a:1024180101032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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