Article
Nonmuscle myosin, force maintenance, and the tonic contractile phenotype in smooth muscle.
Pflugers Archiv : European journal of physiology - 1 Sept 2006
Rhee Albert Y, Ogut Ozgur, Brozovich Frank V
Abstract excerpt
Recent studies have demonstrated that nonmuscle (NM) myosin II forms filaments and can generate and maintain force in smooth muscle tissue [Lofgren et al. (2003) J Gen Physiol 121:301-310; Morano et al. (2000) Nat Cell Biol 2:371-375]. To further investigate the mechanical contribution of NM myosin to force maintenance during smooth muscle contraction, we utilized a selective inhibitor of the NM myosin ATPase,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
