Article
Endothelin-1 alters the contractile phenotype of cultured embryonic smooth muscle cells.
Circulation research - 1 Jun 1997
Fisher S A, Ikebe M, Brozovich F
Abstract excerpt
Smooth muscle tissues may be classified into phasic (fast) or tonic (slow) contractile phenotypes. This study was initiated to examine the specification of these phenotypes during development and the role of growth factors in this process. We used myosin light chain 17 (MLC17) and myosin heavy chain transcript splice variants as markers of the tonic (aortic) and phasic (intestinal) smooth muscle phenotypes in...
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