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Article

Molecular mechanisms of phenotypic plasticity in smooth muscle cells.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Jan 2001

Halayko A J, Solway J

Abstract excerpt

Morphological, functional, molecular and cell biology studies have revealed a striking multifunctional nature of individual smooth muscle cells (SMC). SMCs manifest phenotypic plasticity in response to changes in environment and functional requirements, acquiring a range of structural and functional properties bounded by two extremes, called "synthetic" and "contractile." Each phenotypic state is characterized by...

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Identifiers

PMID: 11133929
DOI: 10.1152/jappl.2001.90.1.358

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