Drosophila invasive tumors: a model for understanding metastasis.

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Article

Drosophila invasive tumors: a model for understanding metastasis.

Cell cycle (Georgetown, Tex.) - 1 Jan 2004

Woodhouse Elisa C, Liotta Lance A

Abstract excerpt

Inactivation of Drosophila tumor suppressor genes can cause excessive proliferation and, in some cases, neoplastic growth. Neoplastic growth in Drosophila tissues can also be followed by metastasis upon transplantation into hosts or in vivo. Recently, we have shown that metastatic tumors of Drosophila can provide a model in which to identify genes that are involved in the metastatic process.

Topics

Animals
Cell Transformation, Neoplastic
Drosophila
Drosophila Proteins
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor
Humans
Membrane Glycoproteins
Mutation
Neoplasm Invasiveness
Neoplasm Transplantation
Neoplasms, Experimental
Semaphorins
Transforming Growth Factor beta
Tumor Suppressor Proteins

Source

Open in PubMed

Identifiers

PMID: 14657663

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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