Expression level of the nm23 gene in clonal populations of metastatic murine and human neoplasms.

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Article

Expression level of the nm23 gene in clonal populations of metastatic murine and human neoplasms.

Cancer research - 15 Oct 1992

Radinsky R, Weisberg H Z, Staroselsky A N, Fidler I J

Abstract excerpt

The purpose of this study was to determine whether nm23 steady-state mRNA expression levels correlate with metastatic potential of mouse K-1735 melanoma cells, human KM12 colon cancer cells, and human SN12 renal cancer cells. Since neoplasms are heterogeneous and contain subpopulations of cells with different metastatic potentials, we analyzed multiple sets of nonmetastatic and metastatic clones isolated from...

Topics

Alleles
Animals
Clone Cells
Colonic Neoplasms
Gene Deletion
Gene Expression Regulation, Neoplastic
Humans
Hybrid Cells
Kidney Neoplasms
Melanoma, Experimental
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred C3H

Monomeric GTP-Binding Proteins

NM23 Nucleoside Diphosphate Kinases

Neoplasm Metastasis

Neoplasm Proteins

Nucleoside-Diphosphate Kinase

Proteins

Source

Open in PubMed

Identifiers

PMID: 1394207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1394207-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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