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Article

Prognostic significance of foetal-like tyrosine kinase 3 mutation in Egyptian children with acute leukaemia.

International journal of laboratory hematology - 1 Jun 2009

Al-Tonbary Y, Mansour A K, Ghazy H, Elghannam D M, Abd-Elghaffar H A

Abstract excerpt

The foetal like tyrosine kinase 3 mutation (Flt3) gene encodes a tyrosine kinase receptor that regulates proliferation and differentiation of haematopoietic stem cells. In children with acute myelogenous leukaemia (AML), internal tandem duplication of the Flt3 gene (Flt3/ITD) was previously reported and correlated to poor prognosis. Limited data are available about childhood acute lymphoblastic leukaemia (ALL)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18336585
DOI: 10.1111/j.1751-553X.2008.01039.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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