Article
Outcome of Childhood Acute Myeloid Leukemia With FLT3-ITD Mutation: The Experience of Children's Cancer Hospital Egypt, 2007-17.
Clinical lymphoma, myeloma & leukemia - 1 Aug 2020
Semary Samah Fathy, Hammad Mahmoud, Soliman Sonya, Yassen Dina, Gamal Marwa, Albeltagy Doaa, Hamdy Nayera, Mahmoud Sonia
Abstract excerpt
INTRODUCTION: The presence of FMS-like tyrosine kinase 3 (FLT3) internal tandem duplication (ITD) mutation in pediatric acute myeloid leukemia (AML) is associated with high rates of induction failure and worse survival. Its presence places the patient into a high-risk group. We aimed to describe the outcome of pediatric AML with FLT3-ITD mutation. PATIENTS AND METHODS: We performed a retrospective analysis of...
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