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Article

Clinical relevance of internal tandem duplication of the FLT3 gene in childhood acute myeloid leukemia.

Cancer - 15 Jun 2002

Liang Der-Cherng, Shih Lee-Yung, Hung Iou-Jih, Yang Chao-Ping, Chen Shu-Huey, Jaing Tang-Her, Liu Hsi-Che, Chang Wan-Hui

Abstract excerpt

BACKGROUND: Recently, an internal tandem duplication of the FLT3 gene (FLT3/ITD) was found in approximately 20% of adult acute myeloid leukemia (AML) cases and associated with a poor outcome. However, there are few studies on FLT3/ITD in childhood AML, and the clinical significance of FLT3/ITD is thus unclear. METHODS: FLT3/ITD was analyzed in 80 children with de novo AML. The genomic DNA polymerase chain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12115363
DOI: 10.1002/cncr.10598

Genes

FLT3
PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Clinical relevance of internal tandem duplication of the FLT3 gene in childhood acute myeloid leukemia.PMID 12115363Read ↗

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