The colony-stimulating factor 1 receptor: pleiotropy of signal-response coupling.

Article

The colony-stimulating factor 1 receptor: pleiotropy of signal-response coupling.

Lymphokine research - 1 Jan 1990

Sherr C J

Abstract excerpt

The colony-stimulating factor 1 receptor (CSF-1R) is a cell surface glycoprotein consisting of an extracellular ligand-binding domain, a single membrane-spanning segment, and an intracellular tyrosine kinase domain. Binding of CSF-1 activates the receptor kinase, leading to "autophosphorylation"...

Topics

Animals
Cell Differentiation
Cell Division
Macrophage Colony-Stimulating Factor
Mitogens
Phenotype
Receptors, Colony-Stimulating Factor
Signal Transduction

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