Article
Identification of tyrosine 706 in the kinase insert as the major colony-stimulating factor 1 (CSF-1)-stimulated autophosphorylation site in the CSF-1 receptor in a murine macrophage cell line.
Molecular and cellular biology - 1 Jun 1990
van der Geer P, Hunter T
Abstract excerpt
The receptor for colony-stimulating factor 1 (CSF-1) is a ligand-activated protein-tyrosine kinase. It has been shown previously that the CSF-1 receptor is phosphorylated on serine in vivo and that phosphorylation on tyrosine can be induced by stimulation with CSF-1. We studied the phosphorylatio...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Cell Line
- Colony-Stimulating Factors
- Macrophage Colony-Stimulating Factor
- Macrophages
- Mice
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Oligopeptides
- Peptide Hydrolases
- Peptide Mapping