Article
Identification of the functional domains of the transcriptional regulator CRE-BP1.
The Journal of biological chemistry - 25 Sept 1991
Matsuda S, Maekawa T, Ishii S
Abstract excerpt
We present evidence that CRE-BP1 binding to the cyclic AMP (cAMP) response element (CRE) is a transcriptional activator. Transcriptional activation was assayed by cotransfection into CV-1 cells of a CRE-BP1 expression plasmid together with a reporter plasmid in which the thymidine kinase promoter and four tandem repeats of CRE were linked to the chloramphenicol acetyltransferase (CAT) gene. Cotransfection with...
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