Article
Dominant negative mutants of transcription factor mXBP (CRE-BP1, ATF-2).
The New biologist - 1 Apr 1992
Ivashkiv L B, Fleming M D, Glimcher L H
Abstract excerpt
Transcription factors of the CREB/ATF family bind to a consensus DNA sequence TGACGTCA (cyclic AMP response element) found in the promoters of numerous genes. Transcriptional activation by one of these proteins, CREB, has been extensively analyzed, but the function of the other family members is...
Topics
- Activating Transcription Factors
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Blood Proteins
- DNA
- Genes, Dominant
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Promoter Regions, Genetic
- Transcription Factors
- Transcriptional Activation