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Article

Identification and characterization of a novel transcriptional activation domain in the CREB-binding protein.

The Journal of biological chemistry - 26 Jul 1996

Bisotto S, Minorgan S, Rehfuss R P

Abstract excerpt

The CREB-binding protein (CBP) plays a central role in the regulation of gene expression by several different second messenger pathways including serum growth factors, cAMP and phorbol esters. CBP specifically binds to the phosphorylated forms of CREB and c-Jun and is thought to activate transcription through a C-terminal activation domain. In this report, we demonstrate that the C terminus of CBP is dispensable...

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Source

Identifiers

PMID: 8663603
DOI: 10.1074/jbc.271.30.17746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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