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Article

Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients.

Journal of psychiatry & neuroscience : JPN - 1 Mar 2008

Lotrich Francis E, Pollock Bruce G, Kirshner Margaret, Ferrell Robert F, Reynolds Iii Charles F

Abstract excerpt

OBJECTIVE: To investigate whether variable antidepressant response may be influenced by an interaction between the serotonin transporter promoter polymorphism (5-HTTLPR) and antidepressant concentration. METHODS: Elderly subjects with depression treated with paroxetine (n = 110) were genotyped an...

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PMID: 18330458
PMCID: PMC2265313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18330458-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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