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Article

Pharmacogenomic implications of variants of monoaminergic-related genes in geriatric psychiatry.

Pharmacogenomics - 1 Sept 2010

Shiroma Paulo R, Geda Yonas E, Mrazek David A

Abstract excerpt

Response to psychiatric medications in later life is highly heterogeneous and complex. Monoaminergic-related polymorphisms may influence medication response and susceptibility to side effects in elderly individuals. Individuals with the lower function short (S) allele of the serotonin transporter gene (SLC6A4) insertion/deletion (indel) promoter polymorphism (5-HTTLPR) have both increased the likelihood of...

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Identifiers

PMID: 20860469
DOI: 10.2217/pgs.10.118

Genes

DRD2
DRD3

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