Article
Thymus-independent type 2 antigen induces a long-term IgG-related network memory.
Molecular immunology - 1 May 2008
Lange Hans, Zemlin Michael, Tanasa Radu Iulian, Trad Ahmad, Weiss Thomas, Menning Hauke, Lemke Hilmar
Abstract excerpt
Thymus-independent type 2 (TI-2) antigens occasionally induce long-lasting IgM memory, but do not prime for typical secondary IgG responses. However, contrary to current understanding, we detected several TI-2-induced long-term memory effects in subsequent thymus-dependent (TD) responses to the hapten 2-phenyloxazolone coupled to a protein carrier. The early primary TD response, even 3 months after TI-2...
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