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Article

Recruiting memory B cells with changed antigenic specificity.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 1993

Ellenberger J, Creadon G, Zhang X, Wysocki L J

Abstract excerpt

During T cell-dependent antibody responses, the V region genes of responding B lymphocytes are physiologically mutated at a high rate. An intense selection process expands subclones of B cells producing mutant antibodies that bind Ag optimally. This implies that most mutant B cells and their antibody products are unselected and not often observed by conventional hybridoma or serum sampling procedures. Herein we...

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PMID: 7693808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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