Article
A mitotic recombination system for mouse chromosome 17.
Proceedings of the National Academy of Sciences of the United States of America - 18 Mar 2008
Sun Lei, Wu Xiaohui, Han Min, Xu Tian, Zhuang Yuan
Abstract excerpt
Mitotic recombination between homologous chromosomes is a genetic technique for mosaic analysis in model organisms. The general application of this technique in the mouse depends on establishment of effective recombination systems for individual chromosomes and reliable and sensitive methods for detection of recombination events. Here, we established a Cre/LoxP-mediated recombination system in mice for mosaic...
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