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Article

Engineering a mouse balancer chromosome.

Nature genetics - 1 Aug 1999

Zheng B, Sage M, Cai W W, Thompson D M, Tavsanli B C, Cheah Y C, Bradley A

Abstract excerpt

Balancer chromosomes are genetic reagents that are used in Drosophila melanogaster for stock maintenance and mutagenesis screens. Despite their utility, balancer chromosomes are rarely used in mice because they are difficult to generate using conventional methods. Here we describe the engineering of a mouse balancer chromosome with the Cre-loxP recombination system. The chromosome features a 24-centiMorgan (cM)...

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Source

Identifiers

PMID: 10431243
DOI: 10.1038/11949

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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