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Article

Induced mitotic recombination of p53 in vivo.

Proceedings of the National Academy of Sciences of the United States of America - 13 Mar 2007

Wang Wei, Warren Madhuri, Bradley Allan

Abstract excerpt

Genetic mosaics produced by FLP/FRT induced mitotic recombination have been widely used in Drosophila to study gene function in development. Recently, the Cre/loxP system has been applied to induce mitotic recombination in mouse embryonic stem cells and in many adult mouse tissues. We have used this strategy to generate a previously undescribed p53 mouse model in which expression of a ubiquitously expressed...

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Identifiers

PMID: 17360553
DOI: 10.1073/pnas.0607953104
PMCID: PMC1838630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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