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Article

Clinical presentation of atopic dermatitis by filaggrin gene mutation status during the first 7 years of life in a prospective cohort study.

PloS one - 1 Jan 2012

Carson Charlotte Giwercman, Rasmussen Morten Arendt, Thyssen Jacob P, Menné Torkil, Bisgaard Hans

Abstract excerpt

BACKGROUND: Filaggrin null mutations result in impaired skin barrier functions, increase the risk of early onset atopic dermatitis and lead to a more severe and chronic disease. We aimed to characterize the clinical presentation and course of atopic dermatitis associated with filaggrin mutations within the first 7 years of life. METHOD: The COPSAC cohort is a prospective, clinical birth cohort study of 411...

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Identifiers

PMID: 23166590
DOI: 10.1371/journal.pone.0048678
PMCID: PMC3499508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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