Article
The alpha 2C Del322-325 adrenergic receptor polymorphism is not associated with heart failure due to idiopathic dilated cardiomyopathy in black Africans.
Cardiovascular journal of Africa - 1 Jan 2000
Du Preez J, Matolweni L O, Greenberg J, Mntla P, Adeyemo A A, Mayosi B M
Abstract excerpt
BACKGROUND: A four-amino acid deletion was identified within the alpha 2C-adrenergic receptor (alpha 2C Del322-325) that, when homozygous, increases the risk of heart failure in African-Americans nearly six-fold. We hypothesised that homozygosity for the alpha 2C Del322-325 polymorphism may be a...
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