Article
No positive association between adrenergic receptor variants of alpha2cDel322-325, beta1Ser49, beta1Arg389 and the risk for heart failure in the Japanese population.
British journal of clinical pharmacology - 1 Oct 2005
Nonen Shinpei, Okamoto Hiroshi, Akino Masatoshi, Matsui Yutaka, Fujio Yasushi, Yoshiyama Minoru, Takemoto Yasuhiko, Yoshikawa Junichi, Azuma Junichi, Kitabatake Akira
Abstract excerpt
AIMS: We investigated the correlation of adrenergic receptor polymorphisms, alpha(2c)Del322-325, beta(1)Ser49Gly and beta(1)Arg389Gly, with the risk of heart failure in the Japanese population. METHODS: These polymorphisms were analysed by polymerase chain reaction-restriction fragment length polymorphism in patients with chronic heart failure due to idiopathic dilated cardiomyopathy (DCM) and compared with the...
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