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Polymorphisms of APOE and LRP genes in Brazilian individuals with Alzheimer disease.

Alzheimer disease and associated disorders - 1 Jan 2000

Bahia Valéria Santoro, Kok Fernando, Marie Suely Nagahashi, Shinjo Sueli Oba, Caramelli Paulo, Nitrini Ricardo

Abstract excerpt

Alzheimer disease (AD) is the most frequent cause of dementia in Western countries. Putative genetic risk factors for AD are polymorphisms in the apolipoprotein E (APOE) gene and in the low-density lipoprotein receptor-related protein (LRP) gene. Our objective was to investigate the role of the APOE coding region polymorphisms epsilon 2, epsilon 3, and epsilon 4 and APOE promoter variants A/T at position -491 and...

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Source

Identifiers

PMID: 18317248
DOI: 10.1097/WAD.0b013e31815a9da7

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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