Article
Association of apolipoprotein E polymorphism in late-onset Alzheimer's disease and vascular dementia in Brazilians.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jul 2003
Souza D R S, de Godoy M R, Hotta J, Tajara E H, Brandão A C, Pinheiro Júnior S, Tognola W A, dos Santos J E
Abstract excerpt
The genetic basis for dementias is complex. A common polymorphism in the apolipoprotein E (APOE) gene is considered to be the major risk factor in families with sporadic and late-onset Alzheimer's disease as well as in the general population. The distribution of alleles and genotypes of the APOE...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Case-Control Studies
- Dementia, Vascular
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans