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Article

Influence of RGS2 on anxiety-related temperament, personality, and brain function.

Archives of general psychiatry - 1 Mar 2008

Smoller Jordan W, Paulus Martin P, Fagerness Jesen A, Purcell Shaun, Yamaki Lesley H, Hirshfeld-Becker Dina, Biederman Joseph, Rosenbaum Jerrold F, Gelernter Joel, Stein Murray B

Abstract excerpt

CONTEXT: Although anxiety disorders are heritable, their genetic and phenotypic complexity has made the identification of susceptibility genes difficult. Well-validated animal models and intermediate phenotypes provide crucial tools for genetic dissection of anxiety. The gene encoding regulator of G protein signaling 2 (Rgs2) is a quantitative trait gene that influences mouse anxiety behavior, making its human...

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Source

Identifiers

PMID: 18316676
DOI: 10.1001/archgenpsychiatry.2007.48

Genes

RGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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