Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rgs 2 gene polymorphisms as modulators of anxiety in humans?

Journal of neural transmission (Vienna, Austria : 1996) - 1 Dec 2006

Leygraf A, Hohoff C, Freitag C, Willis-Owen S A G, Krakowitzky P, Fritze J, Franke P, Bandelow B, Fimmers R, Flint J, Deckert J

Abstract excerpt

Rgs2 (regulator of G-protein signalling 2) gene recently was reported as a quantitative trait gene for anxious behaviour in mice and male Rgs2 knockout mice have been shown to be more anxious than wildtype mice. Therefore we investigated four non-coding single nucleotide polymorphisms in a sample of 173 patients with panic disorder and 173 matched controls of German descent. At the genotype level all four SNPs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anxiety
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Odds Ratio

Share to Panic Disorder

Share to Psychiatric Status Rating Scales

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to RGS Proteins

Source

Identifiers

PMID: 16736243
DOI: 10.1007/s00702-006-0484-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rgs 2 gene polymorphisms as modulators of anxiety in humans?PMID 16736243Read ↗

RGS2 ggenetic variation: association analysis with panic disorder and dimensional as well as intermediate phenotypes of anxiety.Semantic proximity Read ↗

Association analysis of Rgs7 variants with panic disorder.Semantic proximity Read ↗

Association study of RGS2 gene polymorphisms with panic disorder in Japanese.Semantic proximity Read ↗

MicroRNA hsa-miR-4717-5p regulates RGS2 and may be a risk factor for anxiety-related traits.Semantic proximity Read ↗

Association of RGS2 variants with panic disorder in a Japanese population.Semantic proximity Read ↗

GLRB allelic variation associated with agoraphobic cognitions, increased startle response and fear network activation: a potential neurogenetic pathway to panic disorder.Semantic proximity Read ↗

Genetics of panic disorder: focus on association studies and therapeutic perspectives.Semantic proximity Read ↗

Genetic variations of regulator of G-protein signaling 2 in hypertensive patients and in the general population.Semantic proximity Read ↗

Genetics of anxiety disorders - status quo and quo vadis.Semantic proximity Read ↗

RGS2 and generalized anxiety disorder in an epidemiologic sample of hurricane-exposed adults.Semantic proximity Read ↗

Relationship between Rgs2 gene expression level and anxiety and depression-like behaviour in a mutant mouse model: serotonergic involvement.Semantic proximity Read ↗

Genetic factors in anxiety disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.