Article
Variant in RGS2 moderates posttraumatic stress symptoms following potentially traumatic event exposure.
Journal of anxiety disorders - 1 Apr 2009
Amstadter Ananda B, Koenen Karestan C, Ruggiero Kenneth J, Acierno Ron, Galea Sandro, Kilpatrick Dean G, Gelernter Joel
Abstract excerpt
Polymorphisms in the RGS2 (regulator of G-protein signaling 2) gene were found to be associated with anxious behavior in mice and anxiety in humans. We examined whether rs4606, a single nucleotide polymorphism (SNP) of RGS2, and social support moderated risk for PTSD in an epidemiologic sample. The study examines 607 adults from the 2004 Florida Hurricanes study who returned buccal DNA samples via mail. rs4606...
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